The FDA continues to monitor adverse drug event reports for these products and encourages pet owners and veterinarians to report adverse drug events.If your dog or cat experiences any adverse event while using an isoxazoline product, first consult your veterinarian.What should I do if my pet has an adverse drug event while using an isoxazoline product? These products are approved for the treatment and prevention of flea infestations, and the treatment and control of tick infestations. Some are also approved for treatment and control of ear mite infestations and some gastrointestinal parasite infections, and a few are also approved for prevention of heartworm disease.
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Revolution Plus (selamectin and sarolaner) topical solution for cats.Simparica Trio (sarolaner, moxidectin and pyrantel) tablets for dogs.Credelio (lotilaner) tablets for dogs and cats.Bravecto 1-month (fluralaner) tablets for dogs.Bravecto Plus (fluralaner and moxidectin) topical solution for cats.Bravecto (fluralaner) topical solution for cats and dogs.The FDA-approved drugs in this class are.What products are in the isoxazoline class? Some flea and tick products are regulated by the FDA and some are regulated by the Environmental Protection Agency. You can discuss all options with your veterinarian to choose the right product for your pet. Many products are available for prevention and control of flea and tick infestations.Although most dogs and cats haven’t had neurologic adverse reactions, seizures may occur in animals without a prior history.Isoxazoline products have been associated with neurologic adverse reactions, including muscle tremors, ataxia, and seizures in some dogs and cats.The FDA considers products in the isoxazoline class to be safe and effective for dogs and cats but is providing this information so that pet owners and veterinarians can take it into consideration when choosing flea and tick products for their pets.Although these products can and have been safely used in the majority of dogs and cats, pet owners should consult with their veterinarian to review their patients’ medical histories and determine whether a product in the isoxazoline class is appropriate for their pet.The FDA is alerting pet owners and veterinarians of the potential for neurologic adverse events in dogs and cats when treated with drugs that are in the isoxazoline class.
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